Tau in physiology and pathology
Tau in physiology and pathology
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Key Points
Tauopathies are classified into several groups based on the isoform composition of tau aggregates. The splicing of the gene encoding tau is regulated by multiple factors besides tau mutations.
Tau is a natively unfolded protein that shows no tendency for aggregation by itself. Post-translational modifications may modify the process...
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Full title
Tau in physiology and pathology
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TN_cdi_proquest_miscellaneous_1750431166
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1750431166
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ISSN
1471-003X
E-ISSN
1471-0048
DOI
10.1038/nrn.2015.1