Single nucleotide polymorphism associations with response and toxic effects in patients with advance...
Single nucleotide polymorphism associations with response and toxic effects in patients with advanced renal-cell carcinoma treated with first-line sunitinib: a multicentre, observational, prospective study
About this item
Full title
Author / Creator
Garcia-Donas, Jesus, MD , Esteban, Emilio, MD , Leandro-García, Luis Javier, BSc , Castellano, Daniel E, MD , del Alba, Aranzazu González, MD , Climent, Miguel Angel, MD , Arranz, José Angel, MD , Gallardo, Enrique, MD , Puente, Javier, MD , Bellmunt, Joaquim, MD , Mellado, Begoña, MD , Martínez, Esther, MD , Moreno, Fernando, MD , Font, Albert, MD , Robledo, Mercedes, PhD and Rodríguez-Antona, Cristina, Dr
Publisher
England: Elsevier Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: Elsevier Ltd
Subjects
More information
Scope and Contents
Contents
Summary Background Sunitinib is a tyrosine kinase inhibitor with proven efficacy in renal-cell carcinoma, but some patients do not respond or need dose reductions due to toxicity. Because there are no validated molecular predictors of response or toxicity to sunitinib, we aimed to identify genetic markers predictive of outcome and toxic effects. Me...
Alternative Titles
Full title
Single nucleotide polymorphism associations with response and toxic effects in patients with advanced renal-cell carcinoma treated with first-line sunitinib: a multicentre, observational, prospective study
Authors, Artists and Contributors
Author / Creator
Esteban, Emilio, MD
Leandro-García, Luis Javier, BSc
Castellano, Daniel E, MD
del Alba, Aranzazu González, MD
Climent, Miguel Angel, MD
Arranz, José Angel, MD
Gallardo, Enrique, MD
Puente, Javier, MD
Bellmunt, Joaquim, MD
Mellado, Begoña, MD
Martínez, Esther, MD
Moreno, Fernando, MD
Font, Albert, MD
Robledo, Mercedes, PhD
Rodríguez-Antona, Cristina, Dr
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1751215857
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1751215857
Other Identifiers
ISSN
1470-2045
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(11)70266-2
