Anti-angiopoietin therapy with trebananib for recurrent ovarian cancer (TRINOVA-1): a randomised, mu...
Anti-angiopoietin therapy with trebananib for recurrent ovarian cancer (TRINOVA-1): a randomised, multicentre, double-blind, placebo-controlled phase 3 trial
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Author / Creator
Monk, Bradley J, Prof , Poveda, Andrés, MD , Vergote, Ignace, MD , Raspagliesi, Francesco, MD , Fujiwara, Keiichi, MD , Bae, Duk-Soo, MD , Oaknin, Ana, MD , Ray-Coquard, Isabelle, MD , Provencher, Diane M, MD , Karlan, Beth Y, MD , Lhommé, Catherine, MD , Richardson, Gary, MD , Rincón, Dolores Gallardo, MD , Coleman, Robert L, MD , Herzog, Thomas J, MD , Marth, Christian, PhD , Brize, Arija, MD , Fabbro, Michel, MD , Redondo, Andrés, MD , Bamias, Aristotelis, PhD , Tassoudji, Marjan, MS , Navale, Lynn, MS , Warner, Douglas J, MD and Oza, Amit M, MD
Publisher
England: Elsevier Ltd
Journal title
Language
English
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Publication information
Publisher
England: Elsevier Ltd
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Scope and Contents
Contents
Summary Background Angiogenesis is a valid target in the treatment of epithelial ovarian cancer. Trebananib inhibits the binding of angiopoietins 1 and 2 to the Tie2 receptor, and thereby inhibits angiogenesis. We aimed to assess whether the addition of trebananib to single-agent weekly paclitaxel in patients with recurrent epithelial ovarian cance...
Alternative Titles
Full title
Anti-angiopoietin therapy with trebananib for recurrent ovarian cancer (TRINOVA-1): a randomised, multicentre, double-blind, placebo-controlled phase 3 trial
Authors, Artists and Contributors
Author / Creator
Poveda, Andrés, MD
Vergote, Ignace, MD
Raspagliesi, Francesco, MD
Fujiwara, Keiichi, MD
Bae, Duk-Soo, MD
Oaknin, Ana, MD
Ray-Coquard, Isabelle, MD
Provencher, Diane M, MD
Karlan, Beth Y, MD
Lhommé, Catherine, MD
Richardson, Gary, MD
Rincón, Dolores Gallardo, MD
Coleman, Robert L, MD
Herzog, Thomas J, MD
Marth, Christian, PhD
Brize, Arija, MD
Fabbro, Michel, MD
Redondo, Andrés, MD
Bamias, Aristotelis, PhD
Tassoudji, Marjan, MS
Navale, Lynn, MS
Warner, Douglas J, MD
Oza, Amit M, MD
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1751228172
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1751228172
Other Identifiers
ISSN
1470-2045
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(14)70244-X