Tivantinib for second-line treatment of advanced hepatocellular carcinoma: a randomised, placebo-con...
Tivantinib for second-line treatment of advanced hepatocellular carcinoma: a randomised, placebo-controlled phase 2 study
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Author / Creator
Santoro, Armando, MD , Rimassa, Lorenza, Dr , Borbath, Ivan, MD , Daniele, Bruno, MD , Salvagni, Stefania, MD , Van Laethem, Jean Luc, Prof , Van Vlierberghe, Hans, MD , Trojan, Jörg, Prof , Kolligs, Frank T, Prof , Weiss, Alan, Prof , Miles, Steven, MD , Gasbarrini, Antonio, Prof , Lencioni, Monica, MD , Cicalese, Luca, MD , Sherman, Morris, MD , Gridelli, Cesare, MD , Buggisch, Peter, MD , Gerken, Guido, Prof , Schmid, Roland M, Prof , Boni, Corrado, MD , Personeni, Nicola, MD , Hassoun, Ziad, MD , Abbadessa, Giovanni, MD , Schwartz, Brian, MD , Von Roemeling, Reinhard, MD , Lamar, Maria E, BA , Chen, Yinpu, PhD and Porta, Camillo, MD
Publisher
England: Elsevier Ltd
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English
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Publisher
England: Elsevier Ltd
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Contents
Summary Background Tivantinib (ARQ 197), a selective oral inhibitor of MET, has shown promising antitumour activity in hepatocellular carcinoma as monotherapy and in combination with sorafenib. We aimed to assess efficacy and safety of tivantinib for second-line treatment of advanced hepatocellular carcinoma. Methods In this completed, multicentre,...
Alternative Titles
Full title
Tivantinib for second-line treatment of advanced hepatocellular carcinoma: a randomised, placebo-controlled phase 2 study
Authors, Artists and Contributors
Author / Creator
Rimassa, Lorenza, Dr
Borbath, Ivan, MD
Daniele, Bruno, MD
Salvagni, Stefania, MD
Van Laethem, Jean Luc, Prof
Van Vlierberghe, Hans, MD
Trojan, Jörg, Prof
Kolligs, Frank T, Prof
Weiss, Alan, Prof
Miles, Steven, MD
Gasbarrini, Antonio, Prof
Lencioni, Monica, MD
Cicalese, Luca, MD
Sherman, Morris, MD
Gridelli, Cesare, MD
Buggisch, Peter, MD
Gerken, Guido, Prof
Schmid, Roland M, Prof
Boni, Corrado, MD
Personeni, Nicola, MD
Hassoun, Ziad, MD
Abbadessa, Giovanni, MD
Schwartz, Brian, MD
Von Roemeling, Reinhard, MD
Lamar, Maria E, BA
Chen, Yinpu, PhD
Porta, Camillo, MD
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TN_cdi_proquest_miscellaneous_1751228488
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1751228488
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ISSN
1470-2045
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(12)70490-4