Inhibition of TLR4 attenuates vascular dysfunction and oxidative stress in diabetic rats
Inhibition of TLR4 attenuates vascular dysfunction and oxidative stress in diabetic rats
About this item
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Scope and Contents
Contents
Hyperglycemia-induced reactive oxygen species (ROS) production plays a major role in the pathogenesis of diabetic vascular dysfunction. However, the underlying mechanisms remain unclear. Toll-like receptor 4 (TLR4), a key component of innate immunity, is known to be activated during diabetes. Therefore, we hypothesize that hyperglycemia activates T...
Alternative Titles
Full title
Inhibition of TLR4 attenuates vascular dysfunction and oxidative stress in diabetic rats
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Record Identifier
TN_cdi_proquest_miscellaneous_1751229458
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1751229458
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ISSN
0946-2716
E-ISSN
1432-1440
DOI
10.1007/s00109-015-1318-7
