Farnesoid X receptor activation inhibits inflammation and preserves the intestinal barrier in inflam...
Farnesoid X receptor activation inhibits inflammation and preserves the intestinal barrier in inflammatory bowel disease
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Author / Creator
Gadaleta, Raffaella M , van Erpecum, Karel J , Oldenburg, Bas , Willemsen, Ellen C L , Renooij, Willem , Murzilli, Stefania , Klomp, Leo W J , Siersema, Peter D , Schipper, Marguerite E I , Danese, Silvio , Penna, Giuseppe , Laverny, Gilles , Adorini, Luciano , Moschetta, Antonio and Mil, Saskia W C van
Publisher
London: BMJ Publishing Group Ltd and British Society of Gastroenterology
Journal title
Language
English
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Publication information
Publisher
London: BMJ Publishing Group Ltd and British Society of Gastroenterology
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Scope and Contents
Contents
Background & aimsInflammatory bowel disease (IBD) is characterised by chronic intestinal inflammation, resulting from dysregulation of the mucosal immune system and compromised intestinal epithelial barrier function. The bile salt, nuclear farnesoid X receptor (FXR), was recently implicated in intestinal antibacterial defence and barrier function....
Alternative Titles
Full title
Farnesoid X receptor activation inhibits inflammation and preserves the intestinal barrier in inflammatory bowel disease
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Record Identifier
TN_cdi_proquest_miscellaneous_1753460139
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1753460139
Other Identifiers
ISSN
0017-5749
E-ISSN
1468-3288
DOI
10.1136/gut.2010.212159