Retinoblastoma tumorigenesis: genetic and epigenetic changes walk hand in hand
Retinoblastoma tumorigenesis: genetic and epigenetic changes walk hand in hand
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Publisher
England: Future Medicine Ltd
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Language
English
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Publisher
England: Future Medicine Ltd
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Contents
The rate-limiting step in retinoblastoma tumorigenesis is inactivation of both
alleles, but it has remained unclear how this tumor acquires the additional changes that constitute a malignant phenotype. Zhang
characterized the genetic and epigenetic alterations in four retinoblastomas using whole-genome analysis techniques. In these samples, t...
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Retinoblastoma tumorigenesis: genetic and epigenetic changes walk hand in hand
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TN_cdi_proquest_miscellaneous_1753469936
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1753469936
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ISSN
1479-6694
E-ISSN
1744-8301
DOI
10.2217/fon.12.41