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Transgenic expression of the proneural transcription factor Ascl1 in Mueller glia stimulates retinal...

Transgenic expression of the proneural transcription factor Ascl1 in Mueller glia stimulates retinal...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1758242753

Transgenic expression of the proneural transcription factor Ascl1 in Mueller glia stimulates retinal regeneration in young mice

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Full title

Transgenic expression of the proneural transcription factor Ascl1 in Mueller glia stimulates retinal regeneration in young mice

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2015-11, Vol.112 (44), p.13717-13717

Language

English

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Contents

Muller glial cells are the source of retinal regeneration in fish and birds; although this process is efficient in fish, it is less so in birds and very limited in mammals. It has been proposed that factors necessary for providing neurogenic competence to Muller glia in fish and birds after retinal injury are not expressed in mammals. One such fact...

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Full title

Transgenic expression of the proneural transcription factor Ascl1 in Mueller glia stimulates retinal regeneration in young mice

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TN_cdi_proquest_miscellaneous_1758242753

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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1758242753

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ISSN

0027-8424

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