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Polymorphisms of large effect explain the majority of the host genetic contribution to variation of...

Polymorphisms of large effect explain the majority of the host genetic contribution to variation of...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1758245726

Polymorphisms of large effect explain the majority of the host genetic contribution to variation of HIV-1 virus load

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Previous genome-wide association studies (GWAS) of HIV-1–infected populations have been underpowered to detect common variants with moderate impact on disease outcome and have not assessed the phenotypic variance explained by genome-wide additive effects. By combining the majority of available genome-wide genotyping data in HIV-infected populations...

Alternative Titles

Full title

Polymorphisms of large effect explain the majority of the host genetic contribution to variation of HIV-1 virus load

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1758245726

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1758245726

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1514867112

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