Impairment of PARK14-dependent Ca(2+) signalling is a novel determinant of Parkinson's disease
Impairment of PARK14-dependent Ca(2+) signalling is a novel determinant of Parkinson's disease
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England
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English
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England
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The etiology of idiopathic Parkinson's disease (idPD) remains enigmatic despite recent successes in identification of genes (PARKs) that underlie familial PD. To find new keys to this incurable neurodegenerative disorder we focused on the poorly understood PARK14 disease locus (Pla2g6 gene) and the store-operated Ca(2+) signalling pathway. Analysis...
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Impairment of PARK14-dependent Ca(2+) signalling is a novel determinant of Parkinson's disease
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TN_cdi_proquest_miscellaneous_1760853981
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1760853981
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E-ISSN
2041-1723
DOI
10.1038/ncomms10332