Log in to save to my catalogue

Reduced expression of voltage-gated Kv11.1 (hERG) K+ channels in aganglionic colon in Hirschsprung’s...

Reduced expression of voltage-gated Kv11.1 (hERG) K+ channels in aganglionic colon in Hirschsprung’s...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1760854105

Reduced expression of voltage-gated Kv11.1 (hERG) K+ channels in aganglionic colon in Hirschsprung’s disease

About this item

Full title

Reduced expression of voltage-gated Kv11.1 (hERG) K+ channels in aganglionic colon in Hirschsprung’s disease

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Pediatric surgery international, 2016-01, Vol.32 (1), p.9-16

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Purpose
The pathophysiology of Hirschsprung’s disease (HSCR) is not entirely understood. There is no clear explanation for the occurrence of the spastic or tonically contracted aganglionic segment of bowel. Kv11.1 (hERG) channels play a critical role in the regulation of the resting membrane potential as well as affecting either the force or fre...

Alternative Titles

Full title

Reduced expression of voltage-gated Kv11.1 (hERG) K+ channels in aganglionic colon in Hirschsprung’s disease

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1760854105

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1760854105

Other Identifiers

ISSN

0179-0358

E-ISSN

1437-9813

DOI

10.1007/s00383-015-3807-8

How to access this item