A direct approach to amines with remote stereocentres by enantioselective CuH-catalysed reductive re...
A direct approach to amines with remote stereocentres by enantioselective CuH-catalysed reductive relay hydroamination
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Amines with remote stereocentres (stereocentres that are three or more bonds away from the C–N bond) are important structural elements in many pharmaceutical agents and natural products. However, previously reported methods to prepare these compounds in an enantioselective manner are indirect and require multistep synthesis. Here, we report a coppe...
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A direct approach to amines with remote stereocentres by enantioselective CuH-catalysed reductive relay hydroamination
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TN_cdi_proquest_miscellaneous_1760889432
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1760889432
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1755-4330
E-ISSN
1755-4349
DOI
10.1038/nchem.2418
