Efficacy and safety of dupilumab in adults with moderate-to-severe atopic dermatitis inadequately co...
Efficacy and safety of dupilumab in adults with moderate-to-severe atopic dermatitis inadequately controlled by topical treatments: a randomised, placebo-controlled, dose-ranging phase 2b trial
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Author / Creator
Thaçi, Diamant, Prof , Simpson, Eric L, MD , Beck, Lisa A, Prof , Bieber, Thomas, Prof , Blauvelt, Andrew, MD , Papp, Kim, MD , Soong, Weily, MD , Worm, Margitta, Univ-Prof , Szepietowski, Jacek C, Prof , Sofen, Howard, MD , Kawashima, Makoto, Prof , Wu, Richard, PhD , Weinstein, Steven P, MD , Graham, Neil M H, MD , Pirozzi, Gianluca, MD , Teper, Ariel, MD , Sutherland, E Rand, MD , Mastey, Vera, MS , Stahl, Neil, PhD , Yancopoulos, George D, MD and Ardeleanu, Marius, MD
Publisher
England: Elsevier Ltd
Journal title
Language
English
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Publication information
Publisher
England: Elsevier Ltd
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Scope and Contents
Contents
Summary Background Data from early-stage studies suggested that interleukin (IL)-4 and IL-13 are requisite drivers of atopic dermatitis, evidenced by marked improvement after treatment with dupilumab, a fully-human monoclonal antibody that blocks both pathways. We aimed to assess the efficacy and safety of several dose regimens of dupilumab in adul...
Alternative Titles
Full title
Efficacy and safety of dupilumab in adults with moderate-to-severe atopic dermatitis inadequately controlled by topical treatments: a randomised, placebo-controlled, dose-ranging phase 2b trial
Authors, Artists and Contributors
Author / Creator
Simpson, Eric L, MD
Beck, Lisa A, Prof
Bieber, Thomas, Prof
Blauvelt, Andrew, MD
Papp, Kim, MD
Soong, Weily, MD
Worm, Margitta, Univ-Prof
Szepietowski, Jacek C, Prof
Sofen, Howard, MD
Kawashima, Makoto, Prof
Wu, Richard, PhD
Weinstein, Steven P, MD
Graham, Neil M H, MD
Pirozzi, Gianluca, MD
Teper, Ariel, MD
Sutherland, E Rand, MD
Mastey, Vera, MS
Stahl, Neil, PhD
Yancopoulos, George D, MD
Ardeleanu, Marius, MD
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1762364142
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1762364142
Other Identifiers
ISSN
0140-6736
E-ISSN
1474-547X
DOI
10.1016/S0140-6736(15)00388-8
