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New Mechanisms of Flucytosine Resistance in C. glabrata Unveiled by a Chemogenomics Analysis in S. c...

New Mechanisms of Flucytosine Resistance in C. glabrata Unveiled by a Chemogenomics Analysis in S. c...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1762367441

New Mechanisms of Flucytosine Resistance in C. glabrata Unveiled by a Chemogenomics Analysis in S. cerevisiae: e0135110

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Full title

New Mechanisms of Flucytosine Resistance in C. glabrata Unveiled by a Chemogenomics Analysis in S. cerevisiae: e0135110

Journal title

PloS one, 2015-08, Vol.10 (8)

Language

English

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Contents

5-Flucytosine is currently used as an antifungal drug in combination therapy, but fungal pathogens are rapidly able to develop resistance against this drug, compromising its therapeutic action. The understanding of the underlying resistance mechanisms is crucial to deal with this problem. In this work, the S. cerevisiae deletion mutant collection w...

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Full title

New Mechanisms of Flucytosine Resistance in C. glabrata Unveiled by a Chemogenomics Analysis in S. cerevisiae: e0135110

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TN_cdi_proquest_miscellaneous_1762367441

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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1762367441

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E-ISSN

1932-6203

DOI

10.1371/journal.pone.0135110

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