Timing of Hepatocyte Entry into DNA Synthesis after Partial Hepatectomy Is Cell Autonomous
Timing of Hepatocyte Entry into DNA Synthesis after Partial Hepatectomy Is Cell Autonomous
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United States: National Academy of Sciences of the United States of America
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Language
English
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United States: National Academy of Sciences of the United States of America
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After surgical removal of two-thirds of the liver, remaining hepatocytes replicate and restore hepatic mass within 2 weeks. This process must be initiated by signals extrinsic to the hepatocyte, but it remains unclear whether subsequent events leading to DNA synthesis (S phase) are regulated by circulating or locally produced growth factors (a nonc...
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Timing of Hepatocyte Entry into DNA Synthesis after Partial Hepatectomy Is Cell Autonomous
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TN_cdi_proquest_miscellaneous_17633775
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17633775
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.220430497