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Timing of Hepatocyte Entry into DNA Synthesis after Partial Hepatectomy Is Cell Autonomous

Timing of Hepatocyte Entry into DNA Synthesis after Partial Hepatectomy Is Cell Autonomous

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17633775

Timing of Hepatocyte Entry into DNA Synthesis after Partial Hepatectomy Is Cell Autonomous

About this item

Full title

Timing of Hepatocyte Entry into DNA Synthesis after Partial Hepatectomy Is Cell Autonomous

Publisher

United States: National Academy of Sciences of the United States of America

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2000-11, Vol.97 (23), p.12595-12600

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences of the United States of America

More information

Scope and Contents

Contents

After surgical removal of two-thirds of the liver, remaining hepatocytes replicate and restore hepatic mass within 2 weeks. This process must be initiated by signals extrinsic to the hepatocyte, but it remains unclear whether subsequent events leading to DNA synthesis (S phase) are regulated by circulating or locally produced growth factors (a nonc...

Alternative Titles

Full title

Timing of Hepatocyte Entry into DNA Synthesis after Partial Hepatectomy Is Cell Autonomous

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_17633775

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17633775

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.220430497

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