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Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan

Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1765112148

Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan

About this item

Full title

Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan

Publisher

England

Journal title

Nature (London), 2016-02, Vol.530 (7589), p.184-189

Language

English

Formats

Publication information

Publisher

England

More information

Scope and Contents

Contents

Cellular senescence, a stress-induced irreversible growth arrest often characterized by expression of p16(Ink4a) (encoded by the Ink4a/Arf locus, also known as Cdkn2a) and a distinctive secretory phenotype, prevents the proliferation of preneoplastic cells and has beneficial roles in tissue remodelling during embryogenesis and wound healing. Senesc...

Alternative Titles

Full title

Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1765112148

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1765112148

Other Identifiers

E-ISSN

1476-4687

DOI

10.1038/nature16932

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