Altered mesenchymal niche cells impede generation of normal hematopoietic progenitor cells in leukem...
Altered mesenchymal niche cells impede generation of normal hematopoietic progenitor cells in leukemic bone marrow
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Degeneration of normal hematopoietic cells is a shared feature of malignant diseases in the hematopoietic system. Previous studies have shown the exhaustion of hematopoietic progenitor cells (HPCs) in leukemic marrow, whereas hematopoietic stem cells (HSCs) remain functional upon relocation to non-leukemic marrow. However, the underlying cellular m...
Alternative Titles
Full title
Altered mesenchymal niche cells impede generation of normal hematopoietic progenitor cells in leukemic bone marrow
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Record Identifier
TN_cdi_proquest_miscellaneous_1765977273
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1765977273
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ISSN
0887-6924
E-ISSN
1476-5551
DOI
10.1038/leu.2015.210
