IL-6 down-regulates HLA class II expression and IL-12 production of human dendritic cells to impair...
IL-6 down-regulates HLA class II expression and IL-12 production of human dendritic cells to impair activation of antigen-specific CD4 super(+) T cells
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English
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Immunosuppression in tumor microenvironments critically affects the success of cancer immunotherapy. Here, we focused on the role of interleukin (IL)-6/signal transducer and activator of transcription (STAT3) signaling cascade in immune regulation by human dendritic cells (DCs). IL-6-conditioned monocyte-derived DCs (MoDCs) impaired the presenting...
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IL-6 down-regulates HLA class II expression and IL-12 production of human dendritic cells to impair activation of antigen-specific CD4 super(+) T cells
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TN_cdi_proquest_miscellaneous_1765977337
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1765977337
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ISSN
0340-7004
E-ISSN
1432-0851
DOI
10.1007/s00262-015-1791-4
