Evaluation of the Pharmacokinetics of Single- and Multiple-dose Buprenorphine Buccal Film in Healthy...
Evaluation of the Pharmacokinetics of Single- and Multiple-dose Buprenorphine Buccal Film in Healthy Volunteers
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United States: Elsevier Inc
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English
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United States: Elsevier Inc
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Abstract Purpose Buprenorphine, a partial μ-receptor agonist, is approved for the management of moderate to severe pain, but it has low oral bioavailability. Two open-label studies were performed to determine the pharmacokinetic profile of buprenorphine from buccal film formulations of buprenorphine. Methods Both studies enrolled healthy volunteers...
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Evaluation of the Pharmacokinetics of Single- and Multiple-dose Buprenorphine Buccal Film in Healthy Volunteers
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TN_cdi_proquest_miscellaneous_1767068426
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1767068426
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ISSN
0149-2918
E-ISSN
1879-114X
DOI
10.1016/j.clinthera.2015.12.016