Denosumab treated giant cell tumour of bone: a morphological, immunohistochemical and molecular anal...
Denosumab treated giant cell tumour of bone: a morphological, immunohistochemical and molecular analysis of a series
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England: BMJ Publishing Group LTD
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English
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England: BMJ Publishing Group LTD
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AimsDenosumab, a fully human monoclonal antibody directed against RANKL, has recently been introduced in the treatment strategy of giant cell tumour of bone (GCTB). Aim of this study was to investigate the phenotypical modifications induced by denosumab treatment in a series of 15 GCTB.MethodsThe tumours were characterised for histone 3.3 mutations...
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Denosumab treated giant cell tumour of bone: a morphological, immunohistochemical and molecular analysis of a series
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TN_cdi_proquest_miscellaneous_1767079945
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1767079945
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ISSN
0021-9746
E-ISSN
1472-4146
DOI
10.1136/jclinpath-2015-203248