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Denosumab treated giant cell tumour of bone: a morphological, immunohistochemical and molecular anal...

Denosumab treated giant cell tumour of bone: a morphological, immunohistochemical and molecular anal...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1767079945

Denosumab treated giant cell tumour of bone: a morphological, immunohistochemical and molecular analysis of a series

About this item

Full title

Denosumab treated giant cell tumour of bone: a morphological, immunohistochemical and molecular analysis of a series

Publisher

England: BMJ Publishing Group LTD

Journal title

Journal of clinical pathology, 2016-03, Vol.69 (3), p.240-247

Language

English

Formats

Publication information

Publisher

England: BMJ Publishing Group LTD

More information

Scope and Contents

Contents

AimsDenosumab, a fully human monoclonal antibody directed against RANKL, has recently been introduced in the treatment strategy of giant cell tumour of bone (GCTB). Aim of this study was to investigate the phenotypical modifications induced by denosumab treatment in a series of 15 GCTB.MethodsThe tumours were characterised for histone 3.3 mutations...

Alternative Titles

Full title

Denosumab treated giant cell tumour of bone: a morphological, immunohistochemical and molecular analysis of a series

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1767079945

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1767079945

Other Identifiers

ISSN

0021-9746

E-ISSN

1472-4146

DOI

10.1136/jclinpath-2015-203248

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