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Structural basis of lipoprotein signal peptidase II action and inhibition by the antibiotic globomyc...

Structural basis of lipoprotein signal peptidase II action and inhibition by the antibiotic globomyc...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1768559884

Structural basis of lipoprotein signal peptidase II action and inhibition by the antibiotic globomycin

About this item

Full title

Structural basis of lipoprotein signal peptidase II action and inhibition by the antibiotic globomycin

Publisher

United States: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2016-02, Vol.351 (6275), p.876-880

Language

English

Formats

Publication information

Publisher

United States: American Association for the Advancement of Science

More information

Scope and Contents

Contents

With functions that range from cell envelope structure to signal transduction and transport, lipoproteins constitute 2 to 3% of bacterial genomes and play critical roles in bacterial physiology, pathogenicity, and antibiotic resistance. Lipoproteins are synthesized with a signal peptide securing them to the cytoplasmic membrane with the lipoprotein...

Alternative Titles

Full title

Structural basis of lipoprotein signal peptidase II action and inhibition by the antibiotic globomycin

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1768559884

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1768559884

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.aad3747

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