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Recombinant influenza virus expressing HIV-1 p24 capsid protein induces mucosal HIV-specific CD8 T-c...

Recombinant influenza virus expressing HIV-1 p24 capsid protein induces mucosal HIV-specific CD8 T-c...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1768575177

Recombinant influenza virus expressing HIV-1 p24 capsid protein induces mucosal HIV-specific CD8 T-cell responses

About this item

Full title

Recombinant influenza virus expressing HIV-1 p24 capsid protein induces mucosal HIV-specific CD8 T-cell responses

Publisher

Netherlands: Elsevier Ltd

Journal title

Vaccine, 2016-02, Vol.34 (9), p.1172-1179

Language

English

Formats

Publication information

Publisher

Netherlands: Elsevier Ltd

More information

Scope and Contents

Contents

Highlights • Heterologous HIV-1 protein expression from influenza viruses as a vaccine strategy. • The influenza NS-segment was modified to encode whole HIV-1 p24 capsid gene. • Expression of p24 from influenza viruses by heterologous 2A ribosome skip sequences. • Prime-boost immunization induced systemic and mucosal HIV-specific CD8 T-cells. • HIV...

Alternative Titles

Full title

Recombinant influenza virus expressing HIV-1 p24 capsid protein induces mucosal HIV-specific CD8 T-cell responses

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1768575177

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1768575177

Other Identifiers

ISSN

0264-410X

E-ISSN

1873-2518

DOI

10.1016/j.vaccine.2016.01.030

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