Multifunctional role of the transcription factor Blimp-1 in coordinating plasma cell differentiation
Multifunctional role of the transcription factor Blimp-1 in coordinating plasma cell differentiation
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New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Blimp-1 is known to act as a transcriptional repressor by suppressing genes associated with mature and activated germinal center B cells. Busslinger and colleagues show that Blimp-1 can also directly activate gene expression in plasma cells, including those encoding proteins that regulate the production of membrane-bound immunoglobulin versus secre...
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Full title
Multifunctional role of the transcription factor Blimp-1 in coordinating plasma cell differentiation
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TN_cdi_proquest_miscellaneous_1768586632
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1768586632
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ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.3349
