Ethanol-induced neuronal apoptosis in vivo requires BAX in the developing mouse brain
Ethanol-induced neuronal apoptosis in vivo requires BAX in the developing mouse brain
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Author / Creator
Young, C , Klocke, B J , Tenkova, T , Choi, J , Labruyere, J , Qin, Y-Q , Holtzman, D M , Roth, K A and Olney, J W
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
A single episode of ethanol intoxication triggers widespread apoptotic neurodegeneration in the infant rat or mouse brain. The cell death process occurs over a 6–16 h period following ethanol administration, is accompanied by a robust display of caspase-3 enzyme activation, and meets ultrastructural criteria for apoptosis. Two apoptotic pathways (i...
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Full title
Ethanol-induced neuronal apoptosis in vivo requires BAX in the developing mouse brain
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Record Identifier
TN_cdi_proquest_miscellaneous_17704660
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17704660
Other Identifiers
ISSN
1350-9047
E-ISSN
1476-5403
DOI
10.1038/sj.cdd.4401277
