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The C-terminal cytoplasmic tail of hedgehog receptor Patched1 is a platform for E3 ubiquitin ligase...

The C-terminal cytoplasmic tail of hedgehog receptor Patched1 is a platform for E3 ubiquitin ligase...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1770859278

The C-terminal cytoplasmic tail of hedgehog receptor Patched1 is a platform for E3 ubiquitin ligase complexes

About this item

Full title

The C-terminal cytoplasmic tail of hedgehog receptor Patched1 is a platform for E3 ubiquitin ligase complexes

Publisher

New York: Springer US

Journal title

Molecular and cellular biochemistry, 2016-03, Vol.414 (1-2), p.1-12

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

The Sonic hedgehog (Shh) signaling pathway plays a crucial role in cell proliferation and differentiation via Patched1 (Ptc1), a 12-pass transmembrane receptor protein. The C-terminal cytoplasmic tail of Ptc1 can be cleaved to release the 7th intracellular domain (ICD7), whose function is still unclear. In this study, we found that the ICD7 fragmen...

Alternative Titles

Full title

The C-terminal cytoplasmic tail of hedgehog receptor Patched1 is a platform for E3 ubiquitin ligase complexes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1770859278

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1770859278

Other Identifiers

ISSN

0300-8177

E-ISSN

1573-4919

DOI

10.1007/s11010-015-2643-4

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