Cysteine cathepsin proteases: regulators of cancer progression and therapeutic response
Cysteine cathepsin proteases: regulators of cancer progression and therapeutic response
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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In many cancer types cathepsin proteases are upregulated and display altered trafficking and localization. Increased cathepsin expression generally correlates with increased malignancy and poor patient prognosis.
Secretion of cathepsin proteases by cancer cells and infiltrating immune cells into the extracellular space disrupts int...
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Full title
Cysteine cathepsin proteases: regulators of cancer progression and therapeutic response
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TN_cdi_proquest_miscellaneous_1773831940
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1773831940
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ISSN
1474-175X
E-ISSN
1474-1768
DOI
10.1038/nrc4027
