The multifaceted functions of sirtuins in cancer
The multifaceted functions of sirtuins in cancer
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Key Points
Sirtuins are NAD
+
-dependent enzymes that modulate the activities of target proteins, mediate changes in the metabolic status of cells and regulate diseases of ageing, including neurodegeneration, diabetes, cardiovascular diseases and cancer.
Sirtuin 1 (SIRT1) was the first sirtuin to be shown to be involved in cancer. It wa...
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Full title
The multifaceted functions of sirtuins in cancer
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TN_cdi_proquest_miscellaneous_1773832219
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1773832219
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ISSN
1474-175X
E-ISSN
1474-1768
DOI
10.1038/nrc3985