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The multifaceted functions of sirtuins in cancer

The multifaceted functions of sirtuins in cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1773832219

The multifaceted functions of sirtuins in cancer

About this item

Full title

The multifaceted functions of sirtuins in cancer

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Cancer, 2015-10, Vol.15 (10), p.608-624

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Key Points
Sirtuins are NAD
+
-dependent enzymes that modulate the activities of target proteins, mediate changes in the metabolic status of cells and regulate diseases of ageing, including neurodegeneration, diabetes, cardiovascular diseases and cancer.
Sirtuin 1 (SIRT1) was the first sirtuin to be shown to be involved in cancer. It wa...

Alternative Titles

Full title

The multifaceted functions of sirtuins in cancer

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1773832219

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1773832219

Other Identifiers

ISSN

1474-175X

E-ISSN

1474-1768

DOI

10.1038/nrc3985

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