Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/AL...
Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Contents
C9orf72
mutations are the most common cause of amyotrophic lateral sclerosis and frontotemporal dementia. With unbiased screens in
Saccharomyces cerevisiae
, Jovicic
et al
. identified potent modifiers of toxicity of dipeptide repeat proteins produced by unconventional translation of the
C9orf72
repeat expansions, pointing to n...
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Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS
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TN_cdi_proquest_miscellaneous_1773833735
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1773833735
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ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/nn.4085