Type I interferons in anticancer immunity
Type I interferons in anticancer immunity
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Key Points
The type I interferon (IFN) system involves a single form of IFNβ, several variants of IFNα and other less well-characterized IFNs, all of which signal via a heterodimeric IFNα/β receptor 1 (IFNAR1)–IFNAR2 receptor to transactivate IFN-stimulated genes (ISGs). IFNβ also promotes the transactivation of ISGs through homodimeric IFNAR1.<...
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Full title
Type I interferons in anticancer immunity
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TN_cdi_proquest_miscellaneous_1773834074
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1773834074
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ISSN
1474-1733
E-ISSN
1474-1741
DOI
10.1038/nri3845
