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Alterations of the immunosuppressive IL4I1 enzyme activity induced by naturally occurring SNP/mutati...

Alterations of the immunosuppressive IL4I1 enzyme activity induced by naturally occurring SNP/mutati...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1773840402

Alterations of the immunosuppressive IL4I1 enzyme activity induced by naturally occurring SNP/mutations

About this item

Full title

Alterations of the immunosuppressive IL4I1 enzyme activity induced by naturally occurring SNP/mutations

Publisher

London: Nature Publishing Group UK

Journal title

Genes and immunity, 2016-03, Vol.17 (2), p.148-152

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The immunosuppressive phenylalanine oxidase interleukin 4-induced gene 1 (IL4I1), primarily produced by antigen-presenting cells, inhibits T-cell proliferation and promotes the generation of Foxp3
+
regulatory T cells
in vitro.
Highly expressed by tumour-associated macrophages from human cancers, IL4I1 has a potential role in immune eva...

Alternative Titles

Full title

Alterations of the immunosuppressive IL4I1 enzyme activity induced by naturally occurring SNP/mutations

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1773840402

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1773840402

Other Identifiers

ISSN

1466-4879

E-ISSN

1476-5470

DOI

10.1038/gene.2015.55

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