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Plasma cells as an innovative target in autoimmune disease with renal manifestations

Plasma cells as an innovative target in autoimmune disease with renal manifestations

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1774527087

Plasma cells as an innovative target in autoimmune disease with renal manifestations

About this item

Full title

Plasma cells as an innovative target in autoimmune disease with renal manifestations

Author / Creator

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Nephrology, 2016-04, Vol.12 (4), p.232-240

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Key Points
Two independent plasma-cell compartments can secrete pathogenic autoantibodies: short-lived proliferating plasmablasts that reflect B-cell hyperactivity and non-dividing long-lived memory plasma cells
Long-lived memory plasma cells reside in survival niches in the bone marrow and inflamed tissues where they secrete autoantibodies i...

Alternative Titles

Full title

Plasma cells as an innovative target in autoimmune disease with renal manifestations

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1774527087

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1774527087

Other Identifiers

ISSN

1759-5061

E-ISSN

1759-507X

DOI

10.1038/nrneph.2016.20

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