Plasma cells as an innovative target in autoimmune disease with renal manifestations
Plasma cells as an innovative target in autoimmune disease with renal manifestations
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Key Points
Two independent plasma-cell compartments can secrete pathogenic autoantibodies: short-lived proliferating plasmablasts that reflect B-cell hyperactivity and non-dividing long-lived memory plasma cells
Long-lived memory plasma cells reside in survival niches in the bone marrow and inflamed tissues where they secrete autoantibodies i...
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Full title
Plasma cells as an innovative target in autoimmune disease with renal manifestations
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TN_cdi_proquest_miscellaneous_1774527087
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1774527087
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ISSN
1759-5061
E-ISSN
1759-507X
DOI
10.1038/nrneph.2016.20