HIF-P4H-2 deficiency protects against skeletal muscle ischemia-reperfusion injury
HIF-P4H-2 deficiency protects against skeletal muscle ischemia-reperfusion injury
About this item
Full title
Author / Creator
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
More information
Scope and Contents
Contents
We show here that mice hypomorphic for hypoxia-inducible factor prolyl 4-hydroxylase-2 (HIF-P4H-2) (
Hif-p4h-2
gt/gt
), the main regulator of the stability of the HIFα subunits, have normoxic stabilization of HIF-1α and HIF-2α in their skeletal muscles. The size of the capillaries, but not their number, was increased in the skeletal muscle...
Alternative Titles
Full title
HIF-P4H-2 deficiency protects against skeletal muscle ischemia-reperfusion injury
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1775628564
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1775628564
Other Identifiers
ISSN
0946-2716,1432-1440
E-ISSN
1432-1440
DOI
10.1007/s00109-015-1349-0
