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Genetic and Pharmacological Disruption of Neurokinin 1 Receptor Function Decreases Anxiety-Related B...

Genetic and Pharmacological Disruption of Neurokinin 1 Receptor Function Decreases Anxiety-Related B...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17756868

Genetic and Pharmacological Disruption of Neurokinin 1 Receptor Function Decreases Anxiety-Related Behaviors and Increases Serotonergic Function

About this item

Full title

Genetic and Pharmacological Disruption of Neurokinin 1 Receptor Function Decreases Anxiety-Related Behaviors and Increases Serotonergic Function

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2001-02, Vol.98 (4), p.1912-1917

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Alterations in serotonin (5-hydroxytriptamine, 5-HT), norepinephrine, and γ-aminobutyric acid have been linked to the pathophysiology of anxiety and depression, and medications that modulate these neurotransmitters are widely used to treat mood disorders. Recently, the neuropeptide substance P (SP) and its receptor, the neurokinin 1 receptor (NK1R)...

Alternative Titles

Full title

Genetic and Pharmacological Disruption of Neurokinin 1 Receptor Function Decreases Anxiety-Related Behaviors and Increases Serotonergic Function

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_17756868

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17756868

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.041596398

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