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Marked prolongation of porcine renal xenograft survival in baboons through the use of alpha 1,3- gal...

Marked prolongation of porcine renal xenograft survival in baboons through the use of alpha 1,3- gal...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17763023

Marked prolongation of porcine renal xenograft survival in baboons through the use of alpha 1,3- galactosyltransferase gene-knockout donors and the cotransplantation of vascularized thymic tissue

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Full title

Marked prolongation of porcine renal xenograft survival in baboons through the use of alpha 1,3- galactosyltransferase gene-knockout donors and the cotransplantation of vascularized thymic tissue

Journal title

Nature medicine, 2005-01, Vol.11 (1), p.32-34

Language

English

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Scope and Contents

Contents

The use of animal organs could potentially alleviate the critical worldwide shortage of donor organs for clinical transplantation. Because of the strong immune response to xenografts, success will probably depend upon new strategies of immune suppression and induction of tolerance. Here we report our initial results using alpha -1,3-galactosyltrans...

Alternative Titles

Full title

Marked prolongation of porcine renal xenograft survival in baboons through the use of alpha 1,3- galactosyltransferase gene-knockout donors and the cotransplantation of vascularized thymic tissue

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Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_17763023

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17763023

Other Identifiers

ISSN

1078-8956

DOI

10.1038/nm1172

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