Requirement for Caspase-8 in NF-κB Activation by Antigen Receptor
Requirement for Caspase-8 in NF-κB Activation by Antigen Receptor
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Publisher
Washington, DC: American Association for the Advancement of Science
Journal title
Language
English
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Publisher
Washington, DC: American Association for the Advancement of Science
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Scope and Contents
Contents
Caspase-8, a proapoptotic protease, has an essential role in lymphocyte activation and protective immunity. We show that caspase-8 deficiency (CED) in humans and mice specifically abolishes activation of the transcription factor nuclear factor κB (NF-κB) after stimulation through antigen receptors, Fc receptors, or Toll-like receptor 4 in T, B, and...
Alternative Titles
Full title
Requirement for Caspase-8 in NF-κB Activation by Antigen Receptor
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TN_cdi_proquest_miscellaneous_17785414
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17785414
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1104765
