Log in to save to my catalogue

Colitis susceptibility in p47(phox-/-) mice is mediated by the microbiome

Colitis susceptibility in p47(phox-/-) mice is mediated by the microbiome

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1779024461

Colitis susceptibility in p47(phox-/-) mice is mediated by the microbiome

About this item

Full title

Colitis susceptibility in p47(phox-/-) mice is mediated by the microbiome

Publisher

England

Journal title

Microbiome, 2016-04, Vol.4, p.13

Language

English

Formats

Publication information

Publisher

England

More information

Scope and Contents

Contents

Chronic granulomatous disease (CGD) is caused by defects in nicotinamide adenine dinucleotide phosphate oxidase 2 (NOX2) complex subunits (gp91(phox) (a.k.a. Nox2), p47(phox), p67(phox), p22(phox), p40(phox)) leading to reduced phagocyte-derived reactive oxygen species production. Almost half of patients with CGD develop inflammatory bowel disease,...

Alternative Titles

Full title

Colitis susceptibility in p47(phox-/-) mice is mediated by the microbiome

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1779024461

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1779024461

Other Identifiers

ISSN

2049-2618

E-ISSN

2049-2618

DOI

10.1186/s40168-016-0159-0

How to access this item