Colitis susceptibility in p47(phox-/-) mice is mediated by the microbiome
Colitis susceptibility in p47(phox-/-) mice is mediated by the microbiome
About this item
Full title
Author / Creator
Publisher
England
Journal title
Language
English
Formats
Publication information
Publisher
England
Subjects
More information
Scope and Contents
Contents
Chronic granulomatous disease (CGD) is caused by defects in nicotinamide adenine dinucleotide phosphate oxidase 2 (NOX2) complex subunits (gp91(phox) (a.k.a. Nox2), p47(phox), p67(phox), p22(phox), p40(phox)) leading to reduced phagocyte-derived reactive oxygen species production. Almost half of patients with CGD develop inflammatory bowel disease,...
Alternative Titles
Full title
Colitis susceptibility in p47(phox-/-) mice is mediated by the microbiome
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1779024461
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1779024461
Other Identifiers
ISSN
2049-2618
E-ISSN
2049-2618
DOI
10.1186/s40168-016-0159-0
