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The role of sigma-1 receptor and brain-derived neurotrophic factor in the development of diabetes an...

The role of sigma-1 receptor and brain-derived neurotrophic factor in the development of diabetes an...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1780533031

The role of sigma-1 receptor and brain-derived neurotrophic factor in the development of diabetes and comorbid depression in streptozotocin-induced diabetic rats

About this item

Full title

The role of sigma-1 receptor and brain-derived neurotrophic factor in the development of diabetes and comorbid depression in streptozotocin-induced diabetic rats

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Psychopharmacology, 2016-04, Vol.233 (7), p.1269-1278

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Rationale
Depression is highly prevalent in diabetes (DM).
Brain-derived neurotrophic factor
(BDNF) which is mainly regulated by the endoplasmic reticulum chaperon sigma-1 receptor (S1R) plays a relevant role in the development of depression.
Objectives
We studied the dose-dependent efficacy of S1R agonist fluvoxamine (FLU) in the pr...

Alternative Titles

Full title

The role of sigma-1 receptor and brain-derived neurotrophic factor in the development of diabetes and comorbid depression in streptozotocin-induced diabetic rats

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1780533031

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1780533031

Other Identifiers

ISSN

0033-3158

E-ISSN

1432-2072

DOI

10.1007/s00213-016-4209-x

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