The role of sigma-1 receptor and brain-derived neurotrophic factor in the development of diabetes an...
The role of sigma-1 receptor and brain-derived neurotrophic factor in the development of diabetes and comorbid depression in streptozotocin-induced diabetic rats
About this item
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Author / Creator
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
More information
Scope and Contents
Contents
Rationale
Depression is highly prevalent in diabetes (DM).
Brain-derived neurotrophic factor
(BDNF) which is mainly regulated by the endoplasmic reticulum chaperon sigma-1 receptor (S1R) plays a relevant role in the development of depression.
Objectives
We studied the dose-dependent efficacy of S1R agonist fluvoxamine (FLU) in the pr...
Alternative Titles
Full title
The role of sigma-1 receptor and brain-derived neurotrophic factor in the development of diabetes and comorbid depression in streptozotocin-induced diabetic rats
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1780533031
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1780533031
Other Identifiers
ISSN
0033-3158
E-ISSN
1432-2072
DOI
10.1007/s00213-016-4209-x