ESCRT III repairs nuclear envelope ruptures during cell migration to limit DNA damage and cell death
ESCRT III repairs nuclear envelope ruptures during cell migration to limit DNA damage and cell death
About this item
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Publisher
United States: American Association for the Advancement of Science
Journal title
Language
English
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Publication information
Publisher
United States: American Association for the Advancement of Science
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Scope and Contents
Contents
In eukaryotic cells, the nuclear envelope separates the genomic DNA from the cytoplasmic space and regulates protein trafficking between the two compartments. This barrier is only transiently dissolved during mitosis. Here, we found that it also opened at high frequency in migrating mammalian cells during interphase, which allowed nuclear proteins...
Alternative Titles
Full title
ESCRT III repairs nuclear envelope ruptures during cell migration to limit DNA damage and cell death
Authors, Artists and Contributors
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Record Identifier
TN_cdi_proquest_miscellaneous_1781537080
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1781537080
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.aad7611
