MPTP as a Mitochondrial Neurotoxic Model of Parkinson's Disease
MPTP as a Mitochondrial Neurotoxic Model of Parkinson's Disease
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United States: Springer Nature B.V
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English
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United States: Springer Nature B.V
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1-Methy-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is a potent neurotoxin extensively used to model Parkinson's disease (PD). A cascade of deleterous events, in which mitochondria play a pivotal role, drives MPTP neurotoxicity. How mitochondria are affected by MPTP and how their defect contributes to the demise of dopaminergic neurons in this model...
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MPTP as a Mitochondrial Neurotoxic Model of Parkinson's Disease
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TN_cdi_proquest_miscellaneous_17821680
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17821680
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ISSN
0145-479X
E-ISSN
1573-6881
DOI
10.1023/B:JOBB.0000041771.66775.d5
