DNA methylation on N(6)-adenine in mammalian embryonic stem cells
DNA methylation on N(6)-adenine in mammalian embryonic stem cells
About this item
Full title
DNA methylation on N(6)-adenine in mammalian embryonic stem cells
Author / Creator
Publisher
England
Journal title
Nature (London), 2016-04, Vol.532 (7599), p.329-333
Language
English
Formats
Publication information
Publisher
England
Subjects
More information
Scope and Contents
Contents
It has been widely accepted that 5-methylcytosine is the only form of DNA methylation in mammalian genomes. Here we identify N(6)-methyladenine as another form of DNA modification in mouse embryonic stem cells. Alkbh1 encodes a demethylase for N(6)-methyladenine. An increase of N(6)-methyladenine levels in Alkbh1-deficient cells leads to transcript...
Alternative Titles
Full title
DNA methylation on N(6)-adenine in mammalian embryonic stem cells
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1784750411
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1784750411
Other Identifiers
E-ISSN
1476-4687
DOI
10.1038/nature17640
