Daratumumab monotherapy in patients with treatment-refractory multiple myeloma (SIRIUS): an open-lab...
Daratumumab monotherapy in patients with treatment-refractory multiple myeloma (SIRIUS): an open-label, randomised, phase 2 trial
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Author / Creator
Lonial, Sagar, Prof , Weiss, Brendan M, Prof , Usmani, Saad Z, Prof , Singhal, Seema, Prof , Chari, Ajai, Prof , Bahlis, Nizar J, Prof , Belch, Andrew, Prof , Krishnan, Amrita, Prof , Vescio, Robert A, Prof , Mateos, Maria Victoria, Prof , Mazumder, Amitabha, Prof , Orlowski, Robert Z, Prof , Sutherland, Heather J, Prof , Bladé, Joan, Prof , Scott, Emma C, Prof , Oriol, Albert, MD , Berdeja, Jesus, MD , Gharibo, Mecide, Prof , Stevens, Don A, MD , LeBlanc, Richard, Prof , Sebag, Michael, Prof , Callander, Natalie, Prof , Jakubowiak, Andrzej, Prof , White, Darrell, Prof , de la Rubia, Javier, Prof , Richardson, Paul G, Prof , Lisby, Steen, MD , Feng, Huaibao, PhD , Uhlar, Clarissa M, PhD , Khan, Imran, MD , Ahmadi, Tahamtan, MD and Voorhees, Peter M, Prof
Publisher
England: Elsevier Ltd
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Language
English
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Publisher
England: Elsevier Ltd
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Contents
Summary Background New treatment options are needed for patients with multiple myeloma that is refractory to proteasome inhibitors and immunomodulatory drugs. We assessed daratumumab, a novel CD38-targeted monoclonal antibody, in patients with refractory multiple myeloma. Methods In this open-label, multicentre, phase 2 trial done in Canada, Spain,...
Alternative Titles
Full title
Daratumumab monotherapy in patients with treatment-refractory multiple myeloma (SIRIUS): an open-label, randomised, phase 2 trial
Authors, Artists and Contributors
Author / Creator
Weiss, Brendan M, Prof
Usmani, Saad Z, Prof
Singhal, Seema, Prof
Chari, Ajai, Prof
Bahlis, Nizar J, Prof
Belch, Andrew, Prof
Krishnan, Amrita, Prof
Vescio, Robert A, Prof
Mateos, Maria Victoria, Prof
Mazumder, Amitabha, Prof
Orlowski, Robert Z, Prof
Sutherland, Heather J, Prof
Bladé, Joan, Prof
Scott, Emma C, Prof
Oriol, Albert, MD
Berdeja, Jesus, MD
Gharibo, Mecide, Prof
Stevens, Don A, MD
LeBlanc, Richard, Prof
Sebag, Michael, Prof
Callander, Natalie, Prof
Jakubowiak, Andrzej, Prof
White, Darrell, Prof
de la Rubia, Javier, Prof
Richardson, Paul G, Prof
Lisby, Steen, MD
Feng, Huaibao, PhD
Uhlar, Clarissa M, PhD
Khan, Imran, MD
Ahmadi, Tahamtan, MD
Voorhees, Peter M, Prof
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1785215449
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1785215449
Other Identifiers
ISSN
0140-6736
E-ISSN
1474-547X
DOI
10.1016/S0140-6736(15)01120-4