Major histocompatibility complex class I molecules protect motor neurons from astrocyte-induced toxi...
Major histocompatibility complex class I molecules protect motor neurons from astrocyte-induced toxicity in amyotrophic lateral sclerosis
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Expression of MHC class I molecules on motor neurons protects them from astrocyte-induced toxicity in ALS.
Astrocytes isolated from individuals with amyotrophic lateral sclerosis (ALS) are toxic to motor neurons (MNs) and play a non–cell autonomous role in disease pathogenesis. The mechanisms underlying the susceptibility of MNs to cell death re...
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Major histocompatibility complex class I molecules protect motor neurons from astrocyte-induced toxicity in amyotrophic lateral sclerosis
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TN_cdi_proquest_miscellaneous_1785235687
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1785235687
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1078-8956
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1546-170X
DOI
10.1038/nm.4052