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High expression levels of macrophage migration inhibitory factor sustain the innate immune responses...

High expression levels of macrophage migration inhibitory factor sustain the innate immune responses...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1785236126

High expression levels of macrophage migration inhibitory factor sustain the innate immune responses of neonates

About this item

Full title

High expression levels of macrophage migration inhibitory factor sustain the innate immune responses of neonates

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2016-02, Vol.113 (8), p.E997-E1005

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

The vulnerability to infection of newborns is associated with a limited ability to mount efficient immune responses. High concentrations of adenosine and prostaglandins in the fetal and neonatal circulation hamper the antimicrobial responses of newborn immune cells. However, the existence of mechanisms counterbalancing neonatal immunosuppression ha...

Alternative Titles

Full title

High expression levels of macrophage migration inhibitory factor sustain the innate immune responses of neonates

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1785236126

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1785236126

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1514018113

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