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Barrier regulation: tolerance stops at cell death

Barrier regulation: tolerance stops at cell death

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1787960954

Barrier regulation: tolerance stops at cell death

About this item

Full title

Barrier regulation: tolerance stops at cell death

Publisher

New York: Nature Publishing Group US

Journal title

Nature immunology, 2016-04, Vol.17 (4), p.349-350

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The accumulation of intestinal Foxp3
+
regulatory T cells (T
reg
cells) in response to the microbiota is tightly regulated. Epithelial apoptosis inhibits the production of tolerogenic interferon-β by myeloid cells and thereby reduces the frequency of T
reg
cells and lowers the threshold for inflammatory responses.

Alternative Titles

Full title

Barrier regulation: tolerance stops at cell death

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1787960954

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1787960954

Other Identifiers

ISSN

1529-2908

E-ISSN

1529-2916

DOI

10.1038/ni.3418

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