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PGE2 receptor EP3 inhibits water reabsorption and contributes to polyuria and kidney injury in a str...

PGE2 receptor EP3 inhibits water reabsorption and contributes to polyuria and kidney injury in a str...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1788223577

PGE2 receptor EP3 inhibits water reabsorption and contributes to polyuria and kidney injury in a streptozotocin-induced mouse model of diabetes

About this item

Full title

PGE2 receptor EP3 inhibits water reabsorption and contributes to polyuria and kidney injury in a streptozotocin-induced mouse model of diabetes

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Diabetologia, 2016-06, Vol.59 (6), p.1318-1328

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Aims/hypothesis
The first clinical manifestation of diabetes is polyuria. The prostaglandin E
2
(PGE
2
) receptor EP
3
antagonises arginine vasopressin (AVP)-mediated water reabsorption and its expression is increased in the diabetic kidney. The purpose of this work was to study the contribution of EP
3
to diabetic polyur...

Alternative Titles

Full title

PGE2 receptor EP3 inhibits water reabsorption and contributes to polyuria and kidney injury in a streptozotocin-induced mouse model of diabetes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_1788223577

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1788223577

Other Identifiers

ISSN

0012-186X

E-ISSN

1432-0428

DOI

10.1007/s00125-016-3916-5

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