Target-Agnostic Identification of Functional Monoclonal Antibodies Against Klebsiella pneumoniae Mul...
Target-Agnostic Identification of Functional Monoclonal Antibodies Against Klebsiella pneumoniae Multimeric MrkA Fimbrial Subunit
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Author / Creator
Wang, Qun , Chang, Chew-shun , Pennini, Meghan , Pelletier, Mark , Rajan, Saravanan , Zha, Jingying , Chen, Yan , Cvitkovic, Romana , Sadowska, Agnieszka , Thompson, Jenny Heidbrink , Lin, Hung Yu , Barnes, Arnita , Rickert, Keith , Wilson, Susan , Stover, C. Kendall , Dall'Acqua, William F. , Chowdhury, Partha S. and Xiao, Xiaodong
Publisher
United States: Oxford University Press
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Language
English
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United States: Oxford University Press
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Contents
The increasing incidence of Klebsiella pneumoniae infections refractory to treatment with current broad-spectrum antibiotic classes warrants the exploration of alternative approaches, such as antibody therapy and/or vaccines, for prevention and treatment. However, the lack of validated targets shared by spectrums of clinical strains poses a signifi...
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Full title
Target-Agnostic Identification of Functional Monoclonal Antibodies Against Klebsiella pneumoniae Multimeric MrkA Fimbrial Subunit
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TN_cdi_proquest_miscellaneous_1790947428
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1790947428
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ISSN
0022-1899
E-ISSN
1537-6613
DOI
10.1093/infdis/jiw021