A Randomized Trial of Factor VIII and Neutralizing Antibodies in Hemophilia A
A Randomized Trial of Factor VIII and Neutralizing Antibodies in Hemophilia A
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Author / Creator
Peyvandi, Flora , Mannucci, Pier M , Garagiola, Isabella , El-Beshlawy, Amal , Elalfy, Mohsen , Ramanan, Vijay , Eshghi, Peyman , Hanagavadi, Suresh , Varadarajan, Ramabadran , Karimi, Mehran , Manglani, Mamta V , Ross, Cecil , Young, Guy , Seth, Tulika , Apte, Shashikant , Nayak, Dinesh M , Santagostino, Elena , Mancuso, Maria Elisa , Sandoval Gonzalez, Adriana C , Mahlangu, Johnny N , Bonanad Boix, Santiago , Cerqueira, Monica , Ewing, Nadia P , Male, Christoph , Owaidah, Tarek , Soto Arellano, Veronica , Kobrinsky, Nathan L , Majumdar, Suvankar , Perez Garrido, Rosario , Sachdeva, Anupam , Simpson, Mindy , Thomas, Mathew , Zanon, Ezio , Antmen, Bulent , Kavakli, Kaan , Manco-Johnson, Marilyn J , Martinez, Monica , Marzouka, Esperanza , Mazzucconi, Maria G , Neme, Daniela , Palomo Bravo, Angeles , Paredes Aguilera, Rogelio , Prezotti, Alessandra , Schmitt, Klaus , Wicklund, Brian M , Zulfikar, Bulent and Rosendaal, Frits R
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
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Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
In a randomized, multicenter trial involving boys with severe hemophilia A, the incidence of neutralizing antibodies to factor VIII was 87% higher with recombinant factor VIII products than with plasma-derived factor VIII products.
Hemophilia A is an inherited bleeding disorder characterized by plasma deficiency of coagulation factor VIII.
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Alternative Titles
Full title
A Randomized Trial of Factor VIII and Neutralizing Antibodies in Hemophilia A
Authors, Artists and Contributors
Author / Creator
Mannucci, Pier M
Garagiola, Isabella
El-Beshlawy, Amal
Elalfy, Mohsen
Ramanan, Vijay
Eshghi, Peyman
Hanagavadi, Suresh
Varadarajan, Ramabadran
Karimi, Mehran
Manglani, Mamta V
Ross, Cecil
Young, Guy
Seth, Tulika
Apte, Shashikant
Nayak, Dinesh M
Santagostino, Elena
Mancuso, Maria Elisa
Sandoval Gonzalez, Adriana C
Mahlangu, Johnny N
Bonanad Boix, Santiago
Cerqueira, Monica
Ewing, Nadia P
Male, Christoph
Owaidah, Tarek
Soto Arellano, Veronica
Kobrinsky, Nathan L
Majumdar, Suvankar
Perez Garrido, Rosario
Sachdeva, Anupam
Simpson, Mindy
Thomas, Mathew
Zanon, Ezio
Antmen, Bulent
Kavakli, Kaan
Manco-Johnson, Marilyn J
Martinez, Monica
Marzouka, Esperanza
Mazzucconi, Maria G
Neme, Daniela
Palomo Bravo, Angeles
Paredes Aguilera, Rogelio
Prezotti, Alessandra
Schmitt, Klaus
Wicklund, Brian M
Zulfikar, Bulent
Rosendaal, Frits R
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1792373955
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1792373955
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa1516437
