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CD95 and TRAIL receptor-mediated activation of protein kinase C and NF-κB contributes to apoptosis r...

CD95 and TRAIL receptor-mediated activation of protein kinase C and NF-κB contributes to apoptosis r...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17924324

CD95 and TRAIL receptor-mediated activation of protein kinase C and NF-κB contributes to apoptosis resistance in ductal pancreatic adenocarcinoma cells

About this item

Full title

CD95 and TRAIL receptor-mediated activation of protein kinase C and NF-κB contributes to apoptosis resistance in ductal pancreatic adenocarcinoma cells

Publisher

New York: Nature Publishing Group

Journal title

Oncogene, 2001-07, Vol.20 (31), p.4258-4269

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group

More information

Scope and Contents

Contents

The molecular alterations in tumour cells leading to resistance towards apoptosis induced by CD95 and TRAIL-receptors are not fully understood. We report here that the stimulation of the CD95- and TRAIL-resistant human pancreatic adenocarcinoma cell line PancTuI with an agonistic anti-CD95 antibody or TRAIL resulted in activation of protein kinase...

Alternative Titles

Full title

CD95 and TRAIL receptor-mediated activation of protein kinase C and NF-κB contributes to apoptosis resistance in ductal pancreatic adenocarcinoma cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_17924324

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17924324

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/sj.onc.1204559

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