NGS-based BRCA1/2 mutation testing of high-grade serous ovarian cancer tissue: results and conclusio...
NGS-based BRCA1/2 mutation testing of high-grade serous ovarian cancer tissue: results and conclusions of the first international round robin trial
About this item
Full title
Author / Creator
Endris, Volker , Stenzinger, Albrecht , Pfarr, Nicole , Penzel, Roland , Möbs, Markus , Lenze, Dido , Darb-Esfahani, Silvia , Hummel, Michael , Sabine-Merkelbach-Bruse , Jung, Andreas , Lehmann, Ulrich , Kreipe, Hans , Kirchner, Thomas , Büttner, Reinhard , Jochum, Wolfram , Höfler, Gerald , Dietel, Manfred , Weichert, Wilko and Schirmacher, Peter
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
More information
Scope and Contents
Contents
With the approval of olaparib as monotherapy treatment in platinum-sensitive, relapsed high-grade serous ovarian cancer by the European Medical Agency (EMA), comprehensive genotyping of
BRCA1
and
BRCA2
in tumor tissue has become a mandatory pre-therapeutic test. This requires significant advances in routine tumor test methodologies due...
Alternative Titles
Full title
NGS-based BRCA1/2 mutation testing of high-grade serous ovarian cancer tissue: results and conclusions of the first international round robin trial
Authors, Artists and Contributors
Author / Creator
Stenzinger, Albrecht
Pfarr, Nicole
Penzel, Roland
Möbs, Markus
Lenze, Dido
Darb-Esfahani, Silvia
Hummel, Michael
Sabine-Merkelbach-Bruse
Jung, Andreas
Lehmann, Ulrich
Kreipe, Hans
Kirchner, Thomas
Büttner, Reinhard
Jochum, Wolfram
Höfler, Gerald
Dietel, Manfred
Weichert, Wilko
Schirmacher, Peter
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_1793567630
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_1793567630
Other Identifiers
ISSN
0945-6317
E-ISSN
1432-2307
DOI
10.1007/s00428-016-1919-8
