Cyclin E dysregulation and chromosomal instability in endometrial cancer
Cyclin E dysregulation and chromosomal instability in endometrial cancer
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Deregulation of cyclin E, an activator of cyclin-dependent kinase 2 (Cdk2), has been associated with a broad spectrum of human malignancies. Yet the mechanism linking abnormal cyclin E expression to carcinogenesis is largely unknown. The gene encoding the F-box protein hCdc4, a key component of the molecular machinery that targets cyclin E for degr...
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Full title
Cyclin E dysregulation and chromosomal instability in endometrial cancer
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TN_cdi_proquest_miscellaneous_17994728
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_17994728
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/sj.onc.1207560
